Director / Sr. Scientist: Antibody Discovery and Engineering
We are seeking an individual with antibody discovery and engineering experience. The candidate will be a key contributor in developing antibody-based therapeutics to advance the pipeline within QLSF.
Responsibilities:
Advance and improve multi-specific antibody therapeutics selectivity, potency and developability.
Design and optimize antibody display libraries.
Molecular cloning, hybridoma sequencing, sequence analysis, and generating recombinant antibody expression constructs.
Think creatively to generate best-in-class therapeutic leads.
Provide scientific and technical input to guide pipeline development.
Work on multiple protein engineering projects simultaneously and deliver results in a timely manner.
Requirements:
Ph.D. in immunology, molecular biology, cell biology, or biochemistry.
5-10 years experience working in a biotechnology or academic setting focusing on and overseeing discovery, design and antibody engineering using multi-platform technologies.
Deep understanding of antibody structure and biology to generate well-behaved, potent antibody therapeutic leads.
Appropriate skills in antibody characterization including kinetic binding and thermal stability.
Candidates with structural biology and protein modeling is a plus.
Humanization of antibody variable domains is a plus.
Excellent organization skills, planning and record keeping.
Strong motivation with a dedicated work ethic
Evidence of creative problem-solving skills and ability to take on difficult research challenges
Excellent oral presentation and communication skills
Excellent team player, capable of thriving in a fast paced, highly collaborative, dynamic work environment.